isaiah 22:5 For it is a day of trouble, and of treading down, and of perplexity by the Lord GOD of hosts in the valley of vision, breaking down the walls, and of crying to the mountains. - Free Bible Online

      5. trouble . . . by the Lord--that is, sent by or from the Lord (see on Isa 19:15; Lu 21:22-24).
      valley of vision--(See on Isa 22:1). Some think a valley near Ophel is meant as about to be the scene of devastation (compare see on Isa 32:13,14).
      breaking . . . walls--that is, "a day of breaking the walls" of the city.
      crying to the mountains--the mournful cry of the townsmen "reaches" to (MAURER translates, towards) the mountains, and is echoed back by them. JOSEPHUS describes in the very same language the scene at the assault of Jerusalem under Titus. To this the prophecy, probably, refers ultimately. If, as some think, the "cry" is that of those escaping to the mountains, compare Mt 13:14; 24:16, with this.

JFB.