isaiah 53:3 He is despised and rejected of men; a man of sorrows, and acquainted with grief: and we hid as it were our faces from him; he was despised, and we esteemed him not. - Free Bible Online

      3. rejected--"forsaken of men" [GESENIUS]. "Most abject of men." Literally, "He who ceases from men," that is, is no longer regarded as a man [HENGSTENBERG]. (See on Isa 52:14; Isa 49:7).
      man of sorrows--that is, whose distinguishing characteristic was sorrows.
      acquainted with--familiar by constant contact with.
      grief--literally, "disease"; figuratively for all kinds of calamity (Jer 6:14); leprosy especially represented this, being a direct judgment from God. It is remarkable Jesus is not mentioned as having ever suffered under sickness.
      and we hid . . . faces--rather, as one who causes men to hide their faces from Him (in aversion) [MAURER]. Or, "He was as an hiding of the face before it," that is, as a thing before which a man covers his face in disgust [HENGSTENBERG]. Or, "as one before whom is the covering of the face"; before whom one covers the face in disgust [GESENIUS].
      we--the prophet identifying himself with the Jews. See HORSLEY'S view (see on Isa 53:1).
      esteemed . . . not--negative contempt; the previous words express positive.

JFB.